Matt Iseman is an actor, comedian and television host who began his career as a physician. Diagnosed at 30 with rheumatoid arthritis, he shares his story by combining his medical background and standup comedy routine. He has hosted the game shows Scream Play on E! and Casino Night on GSN. He is currently host of the popular show American Ninja Warrior and the new show Live Rescue.

Actor, Comedian & Television Host Matt Iseman Reveals the Physical & Emotional Toll of Arthritis on Americans (& Himself)

Posted
and last updated
Copyright 2025 Scripps Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.