The actress, known for the television series "Charmed" and the movie "Scream," is on a growing list of woman that have accused Hollywood mogul Harvey Weinstein of rape, abuse and other forms of misconduct and has been tweeting about the scandal.
On Thursday, a spokeswoman for the disgraced movie mogul said, "Any allegations of non-consensual sex are unequivocally denied by Mr. Weinstein."
McGowan instagrammed the notification she received from the company, adding: "TWITTER HAS SUSPENDED ME. THERE ARE POWERFUL FORCES AT WORK. BE MY VOICE."
The social network responded with a tweet, clarifying that McGowan's account was temporarily locked because one of her Tweets included a private phone number," which they said violated their Terms of Service.
"She had been tweeting powerfully about sexual harassment and bias in Hollywood, and her own experience as a survivor of sexual assault, and she spoke for many women who felt they couldn't," said Heidi N. Moore, a New York-based business editor, who was among the first to popularize the boycott.
"Twitter seems to be sending a message that they'd rather see us silenced than take real, meaningful action to fix a problem that's plagued Twitter since the beginning ... when Rose McGowan was temporarily blocked by Twitter, that amplified the perception of silencing victims of various forms of abuse. The idea behind the boycott is to show Twitter that silence they seem to prefer, so we wanted to show them what it looks like."
Moore suggested the boycott last 24 hours, and advised users to completely log out of the popular social media platform starting at midnight Eastern Daylight Time. She added that if folks want to keep tweeting they should amplify women's work and voices instead.
McGowan joined in on the boycott, tweeting: "At midnight we RISE."
Male twitter users, like comedian Michael Ian Black and actor Mark Ruffalo, joined in on the movement as well, but there were also female users who questioned the validity of volunteering a silence.
"Some visible users have left the platform, but it hasn't seemed to make Twitter sit up and take notice. This was a different idea for trying to get that message across," said Kelly Ellis, a software engineer from San Francisco, who created the hashtag. "I hope to see some meaningful changes come out of it, including better tools for dealing with dogpile-style harassment."